As cannabis policies become more permissive, there is a reasonable concern that this may increase rates of CUD and contribute further to the incidence of other mental health disorders. However, several strategies can be implemented to offset these harms.
Globally, the bipolar disorder-related prevalent cases, incident cases and number of YLDs all increased from 1990 to 2019. Regionally, the World Health Organization Region of the Americas accounted for the highest estimated YLD number and rate, with the highest age-standardised prevalence rate in 1990 and 2019 and highest EAPC of prevalence. By sociodemographic index (SDI) quintiles, all five SDI regions saw an increase in estimated incident cases. Nationally, New Zealand reported the highest age-standardised rate of incidence, prevalence and YLDs in 1990 and 2019. The most prominent age effect on incidence rate was in those aged 15–19 years. Decreased effects of period on incidence, prevalence and YLD rates was observed overall and in females, not in males. The incidence, prevalence and YLD rates showed an unfavourable trend in the younger cohorts born after 1990, with males reporting a higher cohort risk than females.
To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The aims of this study were to investigate secular trends and distribution of body mass index (BMI) among individuals with bipolar disorders and the general population between 2008 and 2019. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Lived experience adaptation of mental health interventions can help ensure that the intervention is appropriate for the target population. This paper describes a youth-led adaptation of a self-stigma reduction intervention for young adults with bipolar spectrum disorders, that is, Narrative Enhancement and Cognitive Therapy.
Clinical guidelines recommend providing physical activity interventions (PAIs) to people with schizophrenia or bipolar disorder for weight management. However, the cost-effectiveness of PAIs is unknown. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
A large body of evidence has demonstrated that exposure to childhood maltreatment at any stage of development can have long-lasting consequences. It is associated with a marked increase in risk for psychiatric and medical disorders. This review summarizes the literature investigating the effects of childhood maltreatment on disease vulnerability for mood disorders, specifically summarizing cross-sectional and more recent longitudinal studies demonstrating that childhood maltreatment is more prevalent and is associated with increased risk for first mood episode, episode recurrence, greater comorbidities, and increased risk for suicidal ideation and attempts in individuals with mood disorders. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Pharmacological treatment patterns for bipolar disorder have changed during recent years, but for better or worse? To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Family history is an established risk factor for mental illness. The authors sought to investigate whether polygenic scores (PGSs) can complement family history to improve identification of risk for major mood and psychotic disorders. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Medication self-management (MSM) is considered an important aspect of pharmacotherapy and plays an essential role in the treatment of various illnesses. To date, research into the willingness and attitude of psychiatric healthcare providers toward MSM in patients diagnosed with schizophrenia or bipolar disorders during hospitalization is lacking. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Early intervention for people diagnosed with bipolar disorder is a priority, but little is known about how recovery from first episode psychotic mania is experienced by this group. This study aimed to explore the experience of recovery from first episode psychotic mania for people diagnosed with bipolar disorder.
There have been limited prospective investigations of early clinical markers involved in mood regulation and diagnosis change in young patients. This study aimed to evaluate the changes in impulsivity and defence mechanisms in patients with major depressive disorder (MDD) and bipolar disorder (BD) with acute symptoms and remission compared to healthy controls (HC), and possible psychological predictors of diagnosis conversion. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
The rate of comorbid attention-deficit hyperactivity disorder and bipolar disorder far exceeds chance if the two are independent conditions. Explanations for such a high comorbid prevalence and management implications are considered. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Self-management is one of the cornerstones in the treatment of bipolar disorder (BD). Complementing interventions by apps are seen as a good opportunity to support self-management. However, there is insufficient knowledge about understanding the use of health-related applications by consumers with BD for self-management purposes.
In spite of the recent increase in scientific publications showing an expressive interest in studies about social support, there are still scarce publications regarding this thematic and bipolar disorder, mostly when evaluating the individuals in the state of euthymia. Euthymia referred a state that a bipolar patient does not have signs/symptoms of (hipo)mania or depression, thus assessing individuals in this state may reduce response bias. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
For me, the key implication of the study is that people accessing CAMHS, particularly people who experienced inpatient care in adolescence, should be considered for regular review. Once reaching adulthood, screening and assessment for bipolar and psychosis should be available in the adult mental health services. Hopefully, these measures will limit the duration of non-treatment.
Childhood trauma is negatively associated with depression severity in bipolar disorder; however, the underlying mechanisms remain unclear. We investigated whether personality traits (neuroticism, extraversion, openness, agreeableness, conscientiousness) mediate the relationship between childhood trauma and the severity of bipolar depression. To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Attention deficit hyperactivity disorder is a frequent comorbid condition in adults with bipolar disorder. We performed a meta-analysis aimed at assessing sociodemographic and clinical correlates of attention deficit hyperactivity disorder in bipolar disorder.To read the full article, choose Open Athens “Institutional Login” and search for “Midlands Partnership”.
Bipolar disorder may undertake a progressive course in a subset of patients, and research efforts have been made to understand the biological basis underlying this process. This systematic review examined the literature available on biological markers associated with illness progression in bipolar disorder.. To read the full article, log in using your MPFT NHS OpenAthens details.
Bipolar disorder is a highly disruptive and debilitating problem. Mindfulness-based and mindfulness-informed interventions have exponentially emerged as third-generation therapies, applied to a wide spectrum of disorders, including bipolar disorder. However, the reviews and meta-analyses published to date are limited in their conclusions, as they are based on single-group pretest–posttest cohort designs and mostly focused on mindfulness-based interventions. The present review and meta-analysis try to address these limitations, including studies on informed mindfulness, controlled and single-group designs.To read the full article, log in using your MPFT NHS OpenAthens details.
This review underscores the efficacy and tolerability of lamotrigine for the maintenance treatment of bipolar disorder – especially for the prevention of depressive symptoms and episodes – but does not strongly support its use for the prevention of manic episodes. While a clinician might not be comfortable with the use of lithium because of its need for monitoring, its side effects (especially at higher doses), and its quite narrow therapeutic window, the review underscores the value of lithium in preventing mania.
Uncertainty surrounds the risks of lithium use during pregnancy in women with bipolar disorder. The authors sought to provide a critical appraisal of the evidence related to the efficacy and safety of lithium treatment during the peripartum period, focusing on women with bipolar disorder and their offspring.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
Conclusions
Suicidal risks were high in mood disorders: ideation was highest with BD type II, attempts and suicides (especially violent) with BD type I. Several risk factors for suicidal acts differed between BD versus MDD patients.. To read the full article, log in using your MPFT NHS OpenAthens details.
Psychological Medicine; Cambridge Vol. 49, Iss. 13, (Oct 2019): 2177-2185. DOI:10.1017/S003329171800301X
Background
Given its diverse disease courses and symptom presentations, multiple phenotype dimensions with different biological underpinnings are expected with bipolar disorders (BPs). In this study, we aimed to identify lifetime BP psychopathology dimensions. We also explored the differing associations with bipolar I (BP-I) and bipolar II (BP-II) disorders.. To read the full article, log in using your MPFT NHS OpenAthens details.
Open access. Eating disorders are understood to no longer be the remit of lean adolescent girls alone [1], whatever pop culture offerings such as Netflix’s To The Bone might continue to present. Rather, people with eating disorders are much more diverse, often undiagnosed and often suffering in silence. One patient population with a unique but poorly understood vulnerability to eating disorders, as well as obesity and poor physical health, is people with bipolar disorder.
The cerebellum is involved in cognitive processing and emotion control. Cerebellar alterations could explain symptoms of schizophrenia spectrum disorder (SZ) and bipolar disorder (BD). In addition, literature suggests that lithium might influence cerebellar anatomy. Our aim was to study cerebellar anatomy in SZ and BD, and investigate the effect of lithium. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Case report. A 34-year-old man was referred from psychiatry department with a 4-week history of erythematous scaly lesions over his scalp and upper extremities, with associated acneiform eruptions over the face. Historically, the patient was a diagnosed case of type II bipolar disease, receiving lithium carbonate daily for past 6 months. He was not taking any other medication. Clinical examination revealed well-defined erythematous scaly papules and plaques with white semiadherent scales with mild-to moderate induration over the scalp, chest, back and upper extremities (figures 1 and 2). Additionally, he had skin-coloured to erythematous ….... To read the full article, log in using your NHS OpenAthens details.
The care of people with first-episode mania has been overlooked in comparison with the care of patients with other non-affective psychoses, despite evidence suggesting targeted treatments might be of benefit for this patient group. In this Personal View, we outline the general epidemiology of first-episode mania in the context of bipolar disorder, the natural history of mania (with an emphasis on its recurrent nature), current evidence for pharmacological, psychological, and service-level interventions, current guidelines for the treatment of first-episode mania, and provide a patient's point of view of the care pathway. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
Schizophrenia and bipolar disorder are genetically related and their clinical features overlap. Schizophrenia is conceptualised as a neurodevelopmental disorder but the evidence for bipolar disorder is less clear. Cluster-analytic approaches reveal different cognitive profiles within bipolar disorder, possibly reflective of differing neurodevelopmental loads, which are also suggested by recent genetic and neuroimaging studies. Such studies suggest the potential utility of further clinical subcategories in bipolar disorder based on neurodevelopmental load.. To read the full article, log in using your MPFT NHS OpenAthens details.
Conclusions: Web-based resources are increasingly used by patients with bipolar disorder and their family members to educate themselves about the disease and its treatment. Although provider-patient interactions are frequently perceived to be burdened with time constraints, Web-based information sources are considered reliable and helpful. Future research should explore how high-quality websites could be used to empower patients and improve provider-patient interactions with the goal of enhancing shared decision making between patients and providers.
To determine clinical predictors of lithium response in bipolar disorder. . To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Open access journal. Mental health services lack a strong evidence base on the most effective interventions to reduce compulsory admissions. However, some research suggests a positive impact of crisis-planning interventions in which patients are involved in planning for their future care during a mental health crisis.
Open access journal. Basic symptoms, defined as subjectively perceived disturbances in thought, perception and other essential mental processes, have been established as a predictor of psychotic disorders. However, the relationship between basic symptoms and family history of a transdiagnostic range of severe mental illness, including major depressive disorder, bipolar disorder and schizophrenia, has not been examined.
Deenan Edward and Suhana Ahmed on a Scottish study of prescribing lithium bipolar disorder, which identified a clear trend towards decreasing lithium use.
Commentary. People with severe mental illness have higher mortality rates, culminating in about 20 years of lost life compared with that of the general population, and momentum is growing to reduce this inequality.1, 2 In the general population, neighbourhood social context is related to mortality, but whether such patterns also exist for people with severe mental illness has received little attention. Understanding this relationship could allow us to tailor social interventions for this distinctive population. The study by Jayati Das-Munshi and colleagues3 in The Lancet Psychiatry represents a welcome step in that direction, linking higher neighbourhood ethnic density to lower mortality rates among people with severe mental illness from ethnic minority backgrounds. These results raise the intriguing possibility that factors associated with ethnic density might promote longevity among people with severe mental illness.. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
Neighbourhood social context might play a role in modifying mortality outcomes in severe mental illness, but has received little attention to date. Therefore, we aimed to assess in an ethnically diverse and urban location the association of neighbourhood-level characteristics and individual-level factors for all-cause, natural-cause, and unnatural-cause mortality in those with severe mental illness.. Please contact the library to request a copy of this article - http://bit.ly/2HjNDf3
The home environment provided by the caregivers of a child is an influential single factor for development and wellbeing. We aimed to compare the quality of the home environment of children at familial high‐risk of schizophrenia or bipolar disorder with population‐based controls.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Stigma and Health (May 27, 2019). DOI:10.1037/sah0000181
Public stigma continues to present a barrier to recovery for individuals with mental illness. Prior research suggests that biogenetic causal explanations of mental illness increase aspects of stigma, such as social distance. However, most of that research was specific to depression and schizophrenia, and few studies have explored the stigma of bipolar disorder. The present study examined the impact of cause and treatment information on stigma in bipolar disorder.. To read the full article, log in using your NHS OpenAthens details.
More than 90% of people who attempt suicide have a psychiatric diagnosis; however, twin and family studies suggest that the genetic etiology of suicide attempt is partially distinct from that of the psychiatric disorders themselves. The authors present the largest genome-wide association study (GWAS) on suicide attempt, using cohorts of individuals with major depressive disorder, bipolar disorder, and schizophrenia from the Psychiatric Genomics Consortium.. Login at top right hand side of page using your MPFT NHS OpenAthens for full text.
Psychological Medicine; Cambridge Vol. 49, Iss. 8, (Jun 2019): 1299-1307. DOI:10.1017/S0033291718001885
Background: The neurocognitive trajectory in bipolar disorder (BD) is variable, with controversial findings, and most evidence come from cross-sectional studies. We aimed to examine the course of neurocognitive functioning in a sample of euthymic BD patients in comparison with a control group during a 5-year follow-up.. To read the full article, log in using your NHS OpenAthens details.
Open access. Individuals with bipolar disorder respond to affective symptoms with a range of coping behaviours, which may further maintain the symptoms.
The association between older‐age bipolar disorder and cognitive impairments may be mediated by vascular burden. The aim of the study was to examine the difference of cognitive function between older people with late‐onset bipolar disorder (LOBD) and early‐onset bipolar disorder (EOBD) by considering rigorous vascular risk burden evaluation, comprehensive cognitive tests, and relevant biochemistry data.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Several depressed patients do not respond to traditional antidepressants. Our aim was to systematically review the effectiveness and safety of pramipexole in unipolar and bipolar depression.. To read the full article, log in using your NHS Athens details. To access full-text: click “Log in/Register” (top right hand side). Click ‘Institutional Login’ then select 'OpenAthens Federation', then ‘NHS England’. Enter your Athens details to view the article.
Dafni Katsampa explores a recent cohort study of risk factors suicide bipolar disorder, which finds significant variation in risk factors in men and women.
This study evaluated the feasibility, acceptability, and preliminary efficacy of psychoeducation plus an automated text messaging intervention (Individualized Texting for Adherence Building–Cardiovascular [iTAB-CV]) to improve adherence to antihypertensives and bipolar disorder medication.. Please contact the library to request a copy of this article - http://bit.ly/1Xyazai