Article,

Specific Features of the Hemostatic System in Covid-19

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CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCES, (2022)

Abstract

This article describes the main clinical characteristics of patients with Covid-19. It's a single-center retrospective cohort study. All COVID-19 patients included in this study were diagnosed according to the guidelines for the diagnosis and treatment of pneumonia caused by infection with the novel coronavirus. All patients had laboratory-confirmed infection with SARS-CoV-2 (real-time RT-PCR specific for SARS-CoV-2 was positive). The value of D- dimer coagulation indices, prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen as well as C-reactive protein, procalcitonin, ferritin in predicting the severity and prognosis of COVID-19 was studied. Dysfunction of blood coagulation and procalcitonin are widely used to assess the risk of bacterial infection and C-reactive protein - an indicator of an acute inflammatory process - was found in almost everyone, more often in severe patients.

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