%0 Journal Article %1 mcginigle_use_2008 %A McGinigle, Katharine L %A Gourlay, Margaret L %A Buchanan, Ian B %D 2008 %J Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America %K Adult, Care Humans, Infections, Intensive Methicillin Morbidity, Resistance, Staphylococcal Staphylococcus Units, aureus %N 11 %P 1717--25 %R 18494098 %T The use of active surveillance cultures in adult intensive care units to reduce methicillin-resistant Staphylococcus aureus-related morbidity, mortality, and costs: a systematic review %U http://www.ncbi.nlm.nih.gov/pubmed/18494098 %V 46 %X Active surveillance cultures (ASCs) are universal or targeted microbiological screening cultures for patients admitted to a hospital. ASCs have been proposed to control the increasing numbers of infections due to multidrug-resistant organisms, but their efficacy and cost-effectiveness are unproven. We conducted a systematic review of the literature pertaining to the use of ASCs and control of methicillin-resistant Staphylococcus aureus (MRSA). We searched relevant journals and the PubMed Medline, Web of Science, CINAHL, and Cochrane Library databases. No randomized, controlled trials were identified. Sixteen observational studies and 4 economic analyses were reviewed. Only 2 of the observational studies had a control group. None of the studies were of good quality. Thus, we identified important gaps in the literature, including a need for a clear definition of ASCs, a clear implementation protocol, and rigorous economic evaluations. Existing evidence may favor the use of ASCs, but the evidence is of poor quality, and definitive recommendations cannot be made.

@article{mcginigle_use_2008, abstract = {Active surveillance cultures {(ASCs)} are universal or targeted microbiological screening cultures for patients admitted to a hospital. {ASCs} have been proposed to control the increasing numbers of infections due to multidrug-resistant organisms, but their efficacy and cost-effectiveness are unproven. We conducted a systematic review of the literature pertaining to the use of {ASCs} and control of methicillin-resistant Staphylococcus aureus {(MRSA).} We searched relevant journals and the {PubMed} Medline, Web of Science, {CINAHL,} and Cochrane Library databases. No randomized, controlled trials were identified. Sixteen observational studies and 4 economic analyses were reviewed. Only 2 of the observational studies had a control group. None of the studies were of good quality. Thus, we identified important gaps in the literature, including a need for a clear definition of {ASCs,} a clear implementation protocol, and rigorous economic evaluations. Existing evidence may favor the use of {ASCs,} but the evidence is of poor quality, and definitive recommendations cannot be made.}, added-at = {2011-03-11T10:05:34.000+0100}, author = {{McGinigle}, Katharine L and Gourlay, Margaret L and Buchanan, Ian B}, biburl = {https://www.bibsonomy.org/bibtex/20b2fe266aec757a1e82c002cf2acd5a5/jelias}, doi = {18494098}, interhash = {bf5277e28dc22200ffa033f42df056c0}, intrahash = {0b2fe266aec757a1e82c002cf2acd5a5}, issn = {1537-6591}, journal = {Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America}, keywords = {Adult, Care Humans, Infections, Intensive Methicillin Morbidity, Resistance, Staphylococcal Staphylococcus Units, aureus}, month = jun, note = {{PMID:} 18494098}, number = 11, pages = {1717--25}, shorttitle = {The use of active surveillance cultures in adult intensive care units to reduce methicillin-resistant Staphylococcus aureus-related morbidity, mortality, and costs}, timestamp = {2011-03-11T10:06:11.000+0100}, title = {The use of active surveillance cultures in adult intensive care units to reduce methicillin-resistant Staphylococcus aureus-related morbidity, mortality, and costs: a systematic review}, url = {http://www.ncbi.nlm.nih.gov/pubmed/18494098}, volume = 46, year = 2008 }