%0 Journal Article %1 Nunez2011 %A Núñez, Eduardo %A Steyerberg, Ewout W %A Núñez, Julio %D 2011 %J Revista española de cardiología %K DataInterpretation EffectModifier EndpointDetermination Epidemiologic Forecasting Humans LogisticModels Models RegressionAnalysis SampleSize Statistical %N 6 %P 501-7 %R 10.1016/j.recesp.2011.01.019 %T Regression modeling strategies. %U http://www.ncbi.nlm.nih.gov/pubmed/21531065 %V 64 %X Multivariable regression models are widely used in health science research, mainly for two purposes: prediction and effect estimation. Various strategies have been recommended when building a regression model: a) use the right statistical method that matches the structure of the data; b) ensure an appropriate sample size by limiting the number of variables according to the number of events; c) prevent or correct for model overfitting; d) be aware of the problems associated with automatic variable selection procedures (such as stepwise), and e) always assess the performance of the final model in regard to calibration and discrimination measures. If resources allow, validate the prediction model on external data. %@ 1579-2242; 0300-8932

@article{Nunez2011, abstract = {Multivariable regression models are widely used in health science research, mainly for two purposes: prediction and effect estimation. Various strategies have been recommended when building a regression model: a) use the right statistical method that matches the structure of the data; b) ensure an appropriate sample size by limiting the number of variables according to the number of events; c) prevent or correct for model overfitting; d) be aware of the problems associated with automatic variable selection procedures (such as stepwise), and e) always assess the performance of the final model in regard to calibration and discrimination measures. If resources allow, validate the prediction model on external data.}, added-at = {2023-02-03T11:44:35.000+0100}, author = {Núñez, Eduardo and Steyerberg, Ewout W and Núñez, Julio}, biburl = {https://www.bibsonomy.org/bibtex/2bb619ef454573afd05e25ede9cbd2d3c/jepcastel}, city = {Servicio de Cardiologia, Hospital Clinico Universitario, INCLIVA, Universitat de Valencia, Espana; Cuore International, Reading, Pennsylvania, Estados Unidos.}, doi = {10.1016/j.recesp.2011.01.019}, interhash = {7b735b6e0643790c05cbf89ad9e44822}, intrahash = {bb619ef454573afd05e25ede9cbd2d3c}, isbn = {1579-2242; 0300-8932}, issn = {1579-2242}, journal = {Revista española de cardiología}, keywords = {DataInterpretation EffectModifier EndpointDetermination Epidemiologic Forecasting Humans LogisticModels Models RegressionAnalysis SampleSize Statistical}, month = {6}, note = {6209<m:linebreak></m:linebreak>CI: Copyright (c) 2011; JID: 0404277; 2011/01/27 [received]; 2011/01/29 [accepted]; 2011/04/29 [aheadofprint]; ppublish;}, number = 6, pages = {501-7}, pmid = {21531065}, timestamp = {2023-02-03T11:44:35.000+0100}, title = {[Regression modeling strategies].}, url = {http://www.ncbi.nlm.nih.gov/pubmed/21531065}, volume = 64, year = 2011 }