%0 Journal Article %1 noauthororeditor %A Pareek, Renu Tyagi | Rekha Kalani | Chandresh %D 2023 %J International Journal on Orange Technologies %K alkaloids, chromatography, drug, extraction, metabolism pharmacological, synthesis, toxic, %N 5 %P 1-16 %T Alkaloids, Biosynthesis and Their Applications %U https://journals.researchparks.org/index.php/IJOT/article/view/4328/4057 %V 5 %X Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral2 and even weakly acidic properties.3 Some synthetic compounds of similar structure may also be termed alkaloids.4 In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.5 Alkaloids are produced by a large variety of organisms including bacteria, fungi, plants, and animals.6 They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography.7 Alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine),8 cholinomimetic (e.g. galantamine),9 vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine),10 antibacterial (e.g. chelerythrine),11 and antihyperglycemic activities (e.g. piperine).12 failed verification Many have found use in traditional or modern medicine, or as starting points for drug discovery. Other alkaloids possess psychotropic (e.g. psilocin) and stimulant activities (e.g. cocaine, caffeine, nicotine, theobromine),13 and have been used in entheogenic rituals or as recreational drugs. Alkaloids can be toxic too (e.g. atropine, tubocurarine).14 Although alkaloids act on a diversity of metabolic systems in humans and other animals, they almost uniformly evoke a bitter taste.15

@article{noauthororeditor, abstract = {Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral[2] and even weakly acidic properties.[3] Some synthetic compounds of similar structure may also be termed alkaloids.[4] In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen, sulfur and, more rarely, other elements such as chlorine, bromine, and phosphorus.[5] Alkaloids are produced by a large variety of organisms including bacteria, fungi, plants, and animals.[6] They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography.[7] Alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine),[8] cholinomimetic (e.g. galantamine),[9] vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine),[10] antibacterial (e.g. chelerythrine),[11] and antihyperglycemic activities (e.g. piperine).[12] [failed verification] Many have found use in traditional or modern medicine, or as starting points for drug discovery. Other alkaloids possess psychotropic (e.g. psilocin) and stimulant activities (e.g. cocaine, caffeine, nicotine, theobromine),[13] and have been used in entheogenic rituals or as recreational drugs. Alkaloids can be toxic too (e.g. atropine, tubocurarine).[14] Although alkaloids act on a diversity of metabolic systems in humans and other animals, they almost uniformly evoke a bitter taste.[15]}, added-at = {2023-11-01T07:59:02.000+0100}, author = {Pareek, Renu Tyagi | Rekha Kalani | Chandresh}, biburl = {https://www.bibsonomy.org/bibtex/25ec6be209496699b27e3e35a60cefafd/researchpark_20}, interhash = {45e9310c113efb6fe88e02e535f4fd2d}, intrahash = {5ec6be209496699b27e3e35a60cefafd}, issn = {2615-8140}, journal = {International Journal on Orange Technologies}, keywords = {alkaloids, chromatography, drug, extraction, metabolism pharmacological, synthesis, toxic,}, language = {english}, month = may, number = 5, pages = {1-16}, timestamp = {2023-11-01T07:59:02.000+0100}, title = {Alkaloids, Biosynthesis and Their Applications}, url = {https://journals.researchparks.org/index.php/IJOT/article/view/4328/4057}, volume = 5, year = 2023 }