Of 20 patients with bronchopulmonary dysplasia (BPD), 17 survived (85\%) and were followed prospectively up to one year post-term. Lower respiratory tract infections occurred in 12 patients (70.5\%), and in 7 (41\%) at least one hospital admission was required. At one year post-term follow-up, 9 patient (52.9\%) continued to present respiratory symptoms, and 5 out of 13 (38.4\%) radiographic changes. Six cases (35\%) presented chronic cor pulmonale. Only 6 children (35\%) showed normal growth, while the others showed deficits in one or more growth parameters. Cerebral palsy occurred in 41\% of the children; 3 cases of severe tetraparesis and 4 of moderately severe palsy (hemiparesis or diplegia). Developmental quotient (DQ) was less than 70 in 6 cases (35\%), from 70-90 in 4 (23.5\%), and greater than 90 in 7 (41\%). The severe neurodevelopmental outcomes were significantly correlated with the presence of important neonatal cerebral pathology (3-4 degrees IVH or periventricular leukomalacia). Retinopathy due to prematurity was diagnosed in 7 patients (41\%), and in 5 it progressed to retrolental fibroplasia. Ten cases (58.8\%) showed strabism, of which 8 had previous eye background involvement. Hearing deficit was not detected in any patient. Esthetic and functional sequelae consisted of scalp eschar (3 cases), post-thoracotomy scar (1 case), pleural drainage scars (3 cases), nasal deformity due to prolonged intubation (1 case), laryngeal stenosis (1 case), and post-tracheostomy stenosis (1 case).(ABSTRACT TRUNCATED AT 250 WORDS)
%0 Journal Article
%1 Zaramella1987
%A Zaramella, P.
%A Benini, F.
%A Barba, B. Dalla
%A Rossetti, A.
%A Zorzi, C.
%D 1987
%J Helv Paediatr Acta
%K Age Factors; Birth Weight; Bronchopulmonary Dysplasia; Cerebral Palsy; Follow-Up Studies; Gestational Age; Humans; Infant; Infant, Newborn; Longitudinal Optic Atrophy; Retinopathy of Prematurity; Strabismus
%N 4
%P 263--271
%T Bronchopulmonary dysplasia: a longitudinal study of 20 cases.
%V 42
%X Of 20 patients with bronchopulmonary dysplasia (BPD), 17 survived (85\%) and were followed prospectively up to one year post-term. Lower respiratory tract infections occurred in 12 patients (70.5\%), and in 7 (41\%) at least one hospital admission was required. At one year post-term follow-up, 9 patient (52.9\%) continued to present respiratory symptoms, and 5 out of 13 (38.4\%) radiographic changes. Six cases (35\%) presented chronic cor pulmonale. Only 6 children (35\%) showed normal growth, while the others showed deficits in one or more growth parameters. Cerebral palsy occurred in 41\% of the children; 3 cases of severe tetraparesis and 4 of moderately severe palsy (hemiparesis or diplegia). Developmental quotient (DQ) was less than 70 in 6 cases (35\%), from 70-90 in 4 (23.5\%), and greater than 90 in 7 (41\%). The severe neurodevelopmental outcomes were significantly correlated with the presence of important neonatal cerebral pathology (3-4 degrees IVH or periventricular leukomalacia). Retinopathy due to prematurity was diagnosed in 7 patients (41\%), and in 5 it progressed to retrolental fibroplasia. Ten cases (58.8\%) showed strabism, of which 8 had previous eye background involvement. Hearing deficit was not detected in any patient. Esthetic and functional sequelae consisted of scalp eschar (3 cases), post-thoracotomy scar (1 case), pleural drainage scars (3 cases), nasal deformity due to prolonged intubation (1 case), laryngeal stenosis (1 case), and post-tracheostomy stenosis (1 case).(ABSTRACT TRUNCATED AT 250 WORDS)
@article{Zaramella1987,
abstract = {Of 20 patients with bronchopulmonary dysplasia (BPD), 17 survived (85\%) and were followed prospectively up to one year post-term. Lower respiratory tract infections occurred in 12 patients (70.5\%), and in 7 (41\%) at least one hospital admission was required. At one year post-term follow-up, 9 patient (52.9\%) continued to present respiratory symptoms, and 5 out of 13 (38.4\%) radiographic changes. Six cases (35\%) presented chronic cor pulmonale. Only 6 children (35\%) showed normal growth, while the others showed deficits in one or more growth parameters. Cerebral palsy occurred in 41\% of the children; 3 cases of severe tetraparesis and 4 of moderately severe palsy (hemiparesis or diplegia). Developmental quotient (DQ) was less than 70 in 6 cases (35\%), from 70-90 in 4 (23.5\%), and greater than 90 in 7 (41\%). The severe neurodevelopmental outcomes were significantly correlated with the presence of important neonatal cerebral pathology (3-4 degrees IVH or periventricular leukomalacia). Retinopathy due to prematurity was diagnosed in 7 patients (41\%), and in 5 it progressed to retrolental fibroplasia. Ten cases (58.8\%) showed strabism, of which 8 had previous eye background involvement. Hearing deficit was not detected in any patient. Esthetic and functional sequelae consisted of scalp eschar (3 cases), post-thoracotomy scar (1 case), pleural drainage scars (3 cases), nasal deformity due to prolonged intubation (1 case), laryngeal stenosis (1 case), and post-tracheostomy stenosis (1 case).(ABSTRACT TRUNCATED AT 250 WORDS)},
added-at = {2014-07-20T09:30:53.000+0200},
author = {Zaramella, P. and Benini, F. and Barba, B. Dalla and Rossetti, A. and Zorzi, C.},
biburl = {https://www.bibsonomy.org/bibtex/2ee5bbbbdb31c0fbf83e287b433d33622/ar0berts},
groups = {public},
interhash = {9e28648ed8b4e6caaf376a208df64e88},
intrahash = {ee5bbbbdb31c0fbf83e287b433d33622},
journal = {Helv Paediatr Acta},
keywords = {Age Factors; Birth Weight; Bronchopulmonary Dysplasia; Cerebral Palsy; Follow-Up Studies; Gestational Age; Humans; Infant; Infant, Newborn; Longitudinal Optic Atrophy; Retinopathy of Prematurity; Strabismus},
number = 4,
pages = {263--271},
pmid = {3443552},
timestamp = {2014-07-20T09:30:53.000+0200},
title = {Bronchopulmonary dysplasia: a longitudinal study of 20 cases.},
username = {ar0berts},
volume = 42,
year = 1987
}