Äntibiotic Susceptibility Patterns in Commonly Isolated Pathogens in East Indian Population"
Advances in Biochemistry and Biotechnology, 7 (1):
1-4 (March 2019)Abstract
Background and Objective: Urinary tract infection is one of the commonest infections seen in clinical practice. Lack of compliance and unjustified antibiotic prescriptions has resulted in bacterial resistance and is proving as a major challenge in the management of these infections. Our aim was to identify the sensitivity pattern of commonly used antibiotics against urinary tract infections in east Indian population of different age groups.
Method: This was a hospital based cross sectional study extended over a period of four months. Patients were recruited from Out-Patients department of a tertiary care hospital in Department of Microbiology, Narayam Medical College and Hospital, Jamuhar, Sasaram, Bihar, India. Adult patients with symptomatic and documented UTI in urine detailed report (pus cells >10) were enrolled after informed consent. Clean catch midstream urine was collected for culture and sensitivity testing using the standard microbiological procedure.
Results: A total of 180 samples were collected in 4 months. The mean age was 48.5±12 years and patients were between 20-80 years. Most common isolated pathogen was Eschericia coli 80 (44.44%) followed by Klebsiella 38 (21.11%), Pseudomonas 24 (13.33%), Proteus 16 (8.88%), Enterococcus 13 (7.22%) Staphylococcus aureus 9 (5%)
Conclusion: In low socioeconomic environment patients with UTI most of the isolated pathogens have shown resistance to most of the commonly used antibiotics recommended in the guidelines probably because of its unwarranted use. Therefore, a revised line of management should be developed locally in accordance with the susceptibility pattern of the urinary pathogens to avoid further resistance as well as morbidity of the patient.