Joint modelling of multivariate longitudinal profiles: pitfalls of the random-effects approach.
S. Fieuws, and G. Verbeke. Statistics in medicine, 23 (20):
3093-104(October 2004)4302<m:linebreak></m:linebreak>PUBM: Print; CI: Copyright 2004; JID: 8215016; ppublish;<m:linebreak></m:linebreak>Mixed models.
DOI: 10.1002/sim.1885
Abstract
Due to its flexibility, the random-effects approach for the joint modelling of multivariate longitudinal profiles received a lot of attention in recent publications. In this approach different mixed models are joined by specifying a common distribution for their random-effects. Parameter estimates of this common distribution can then be used to evaluate the relation between the different responses. Using bivariate longitudinal measurements on pure-tone hearing thresholds, it will be shown that such a random-effects approach can yield misleading results for evaluating this relationship.
%0 Journal Article
%1 Fieuws2004
%A Fieuws, Steffen
%A Verbeke, Geert
%D 2004
%J Statistics in medicine
%K Adolescent Adult Aged Biological HearingLoss Humans LongitudinalStudies Male MiddleAged Models MultivariateAnalysis Statistical
%N 20
%P 3093-104
%R 10.1002/sim.1885
%T Joint modelling of multivariate longitudinal profiles: pitfalls of the random-effects approach.
%U http://www.ncbi.nlm.nih.gov/pubmed/15449333
%V 23
%X Due to its flexibility, the random-effects approach for the joint modelling of multivariate longitudinal profiles received a lot of attention in recent publications. In this approach different mixed models are joined by specifying a common distribution for their random-effects. Parameter estimates of this common distribution can then be used to evaluate the relation between the different responses. Using bivariate longitudinal measurements on pure-tone hearing thresholds, it will be shown that such a random-effects approach can yield misleading results for evaluating this relationship.
%@ 0277-6715
@article{Fieuws2004,
abstract = {Due to its flexibility, the random-effects approach for the joint modelling of multivariate longitudinal profiles received a lot of attention in recent publications. In this approach different mixed models are joined by specifying a common distribution for their random-effects. Parameter estimates of this common distribution can then be used to evaluate the relation between the different responses. Using bivariate longitudinal measurements on pure-tone hearing thresholds, it will be shown that such a random-effects approach can yield misleading results for evaluating this relationship.},
added-at = {2023-02-03T11:44:35.000+0100},
author = {Fieuws, Steffen and Verbeke, Geert},
biburl = {https://www.bibsonomy.org/bibtex/2b2444c34b578a8fb654fa4834364e26d/jepcastel},
city = {Biostatistical Centre, Katholieke Universiteit Leuven, Kapucijnenvoer 35, B-3000 Leuven, Belgium. steffen.fieuws@med.kuleuven.ac.be},
doi = {10.1002/sim.1885},
interhash = {4aaed0afac392164149f5f022743ca5e},
intrahash = {b2444c34b578a8fb654fa4834364e26d},
isbn = {0277-6715},
issn = {0277-6715},
journal = {Statistics in medicine},
keywords = {Adolescent Adult Aged Biological HearingLoss Humans LongitudinalStudies Male MiddleAged Models MultivariateAnalysis Statistical},
month = {10},
note = {4302<m:linebreak></m:linebreak>PUBM: Print; CI: Copyright 2004; JID: 8215016; ppublish;<m:linebreak></m:linebreak>Mixed models},
number = 20,
pages = {3093-104},
pmid = {15449333},
timestamp = {2023-02-03T11:44:35.000+0100},
title = {Joint modelling of multivariate longitudinal profiles: pitfalls of the random-effects approach.},
url = {http://www.ncbi.nlm.nih.gov/pubmed/15449333},
volume = 23,
year = 2004
}