%0 Journal Article %1 10.1371/journal.pbio.3000383 %A Mold, Jeff E. %A Réu, Pedro %A Olin, Axel %A Bernard, Samuel %A Michaëlsson, Jakob %A Rane, Sanket %A Yates, Andrew %A Khosravi, Azadeh %A Salehpour, Mehran %A Possnert, Göran %A Brodin, Petter %A Frisén, Jonas %D 2019 %I Public Library of Science %J PLOS Biology %K T cells %N 10 %P 1-26 %R 10.1371/journal.pbio.3000383 %T Cell generation dynamics underlying naive T-cell homeostasis in adult humans %U https://doi.org/10.1371/journal.pbio.3000383 %V 17 %X Our pool of naive T cells is critical for protection against new infections and cancers. By measuring remnant 14C from 1960s nuclear bomb blasts that has been incorporated into cellular DNA, this study defines the average age of the naive T-cell pool in healthy adults, revealing the slow, regulated turnover of the naive T-cell pool, supporting its maintenance for a human lifetime.

@article{10.1371/journal.pbio.3000383, abstract = {Our pool of naive T cells is critical for protection against new infections and cancers. By measuring remnant 14C from 1960s nuclear bomb blasts that has been incorporated into cellular DNA, this study defines the average age of the naive T-cell pool in healthy adults, revealing the slow, regulated turnover of the naive T-cell pool, supporting its maintenance for a human lifetime.}, added-at = {2020-04-02T20:30:21.000+0200}, author = {Mold, Jeff E. and Réu, Pedro and Olin, Axel and Bernard, Samuel and Michaëlsson, Jakob and Rane, Sanket and Yates, Andrew and Khosravi, Azadeh and Salehpour, Mehran and Possnert, Göran and Brodin, Petter and Frisén, Jonas}, biburl = {https://www.bibsonomy.org/bibtex/2b0508d90f55815deb61a64eb0f988718/lkanth}, description = {Cell generation dynamics underlying naive T-cell homeostasis in adult humans}, doi = {10.1371/journal.pbio.3000383}, interhash = {2a51f0d02fae4062e0d5f2aa5a4436f9}, intrahash = {b0508d90f55815deb61a64eb0f988718}, issn = {1544-9173}, journal = {PLOS Biology}, keywords = {T cells}, month = {10}, number = 10, pages = {1-26}, publisher = {Public Library of Science}, timestamp = {2020-04-02T20:30:21.000+0200}, title = {Cell generation dynamics underlying naive T-cell homeostasis in adult humans}, url = {https://doi.org/10.1371/journal.pbio.3000383}, volume = 17, year = 2019 }