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EVALUATION OF ANTI-HIV-1 ACTIVITY FROM CESTRUM NOCTURNUM AERIAL PARTS AND PHYTOCHEMICAL ANALYSIS

(Eds.) Reviews of Progress, (May 2013)

Abstract

This study deals with evaluation of HIV-1 activity from Cestrum nocturnum aerial parts extracts and investigation of phytoconstituents in the plant extracts. Different extracts fromCestrum nocturnum aerial parts, methanol 80%, ethyl acetate, butanol and aqueous extracts were tested for their anti-HIV-1 activity using the syncytia formation assay. All the extracts were weak active as anti-HIV-1 agents. Phytochemical analysis of Cestrum nocturnum extracts have shown the presence of different phytocomponents, saponins, triterpenes and/or sterols flavonoids, tannins and coumarins. The results confirm that all extracts from Cestrum nocturnumaerial parts have a weak anti-HIV-1 activity.

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