BACKGROUND: A high prevalence of abnormal cerebral MRI findings has been reported in low-birth-weight children. OBJECTIVE: To compare MRI findings in very-low-birth-weight (VLBW) and term small-for-gestational-age (SGA) children with controls in early adolescence. MATERIALS AND METHODS: Cerebral MRI was used to examine 55 VLBW, 54 SGA and 66 controls at 15 years of age. The MR images were qualitatively assessed, and size of ventricles, white-matter and grey-matter abnormalities were reported. RESULTS: The VLBW teenagers had a higher prevalence of various MRI abnormalities than SGA children and controls. Dilation of the ventricular system, especially of the occipital horns, was found in 82\% of the VLBW group, in 19\% of the SGA group and in 21\% of controls. White-matter reduction was found in 53\% of the VLBW, in 6\% of the SGA and in 2\% of controls. Corpus callosum thinning was found in 47\% of the VLBW, in 2\% of the SGA and in 6\% of controls. Periventricular gliosis was found in 29\% of the VLBW, in 4\% of the SGA and in 8\% of controls. CONCLUSIONS: Cerebral MRI pathology in white matter is a common finding in VLBW teenagers. The findings may indicate minor perinatal PVL with resulting loss of white-matter tissue and ventricular dilation.
%0 Journal Article
%1 Skranes2005
%A Skranes, Jon S
%A Martinussen, Marit
%A Smevik, Olaug
%A Myhr, Gunnar
%A Indredavik, Marit
%A Vik, Torstein
%A Brubakk, Ann-Mari
%D 2005
%J Pediatr Radiol
%K Adolescent; Cerebral Palsy; Ventricles; Corpus Callosum; Female; Follow-Up Studies; Gliosis; Humans; Image Processing, Computer-Assisted; Infant, Newborn; Small for Gestational Age; Very Low Birth Weight; Magnetic Resonance Imaging; Male
%N 8
%P 758--765
%R 10.1007/s00247-005-1446-2
%T Cerebral MRI findings in very-low-birth-weight and small-for-gestational-age children at 15 years of age.
%U http://dx.doi.org/10.1007/s00247-005-1446-2
%V 35
%X BACKGROUND: A high prevalence of abnormal cerebral MRI findings has been reported in low-birth-weight children. OBJECTIVE: To compare MRI findings in very-low-birth-weight (VLBW) and term small-for-gestational-age (SGA) children with controls in early adolescence. MATERIALS AND METHODS: Cerebral MRI was used to examine 55 VLBW, 54 SGA and 66 controls at 15 years of age. The MR images were qualitatively assessed, and size of ventricles, white-matter and grey-matter abnormalities were reported. RESULTS: The VLBW teenagers had a higher prevalence of various MRI abnormalities than SGA children and controls. Dilation of the ventricular system, especially of the occipital horns, was found in 82\% of the VLBW group, in 19\% of the SGA group and in 21\% of controls. White-matter reduction was found in 53\% of the VLBW, in 6\% of the SGA and in 2\% of controls. Corpus callosum thinning was found in 47\% of the VLBW, in 2\% of the SGA and in 6\% of controls. Periventricular gliosis was found in 29\% of the VLBW, in 4\% of the SGA and in 8\% of controls. CONCLUSIONS: Cerebral MRI pathology in white matter is a common finding in VLBW teenagers. The findings may indicate minor perinatal PVL with resulting loss of white-matter tissue and ventricular dilation.
@article{Skranes2005,
abstract = {BACKGROUND: A high prevalence of abnormal cerebral MRI findings has been reported in low-birth-weight children. OBJECTIVE: To compare MRI findings in very-low-birth-weight (VLBW) and term small-for-gestational-age (SGA) children with controls in early adolescence. MATERIALS AND METHODS: Cerebral MRI was used to examine 55 VLBW, 54 SGA and 66 controls at 15 years of age. The MR images were qualitatively assessed, and size of ventricles, white-matter and grey-matter abnormalities were reported. RESULTS: The VLBW teenagers had a higher prevalence of various MRI abnormalities than SGA children and controls. Dilation of the ventricular system, especially of the occipital horns, was found in 82\% of the VLBW group, in 19\% of the SGA group and in 21\% of controls. White-matter reduction was found in 53\% of the VLBW, in 6\% of the SGA and in 2\% of controls. Corpus callosum thinning was found in 47\% of the VLBW, in 2\% of the SGA and in 6\% of controls. Periventricular gliosis was found in 29\% of the VLBW, in 4\% of the SGA and in 8\% of controls. CONCLUSIONS: Cerebral MRI pathology in white matter is a common finding in VLBW teenagers. The findings may indicate minor perinatal PVL with resulting loss of white-matter tissue and ventricular dilation.},
added-at = {2014-07-19T21:22:07.000+0200},
author = {Skranes, Jon S and Martinussen, Marit and Smevik, Olaug and Myhr, Gunnar and Indredavik, Marit and Vik, Torstein and Brubakk, Ann-Mari},
biburl = {https://www.bibsonomy.org/bibtex/2686f7aeb081cbeb5718dfdbb4648bc8a/ar0berts},
doi = {10.1007/s00247-005-1446-2},
groups = {public},
interhash = {f49da365fb76954b61ee777c573d8571},
intrahash = {686f7aeb081cbeb5718dfdbb4648bc8a},
journal = {Pediatr Radiol},
keywords = {Adolescent; Cerebral Palsy; Ventricles; Corpus Callosum; Female; Follow-Up Studies; Gliosis; Humans; Image Processing, Computer-Assisted; Infant, Newborn; Small for Gestational Age; Very Low Birth Weight; Magnetic Resonance Imaging; Male},
month = Aug,
number = 8,
pages = {758--765},
pmid = {15864579},
timestamp = {2014-07-19T21:22:07.000+0200},
title = {Cerebral MRI findings in very-low-birth-weight and small-for-gestational-age children at 15 years of age.},
url = {http://dx.doi.org/10.1007/s00247-005-1446-2},
username = {ar0berts},
volume = 35,
year = 2005
}