%0 Journal Article %1 rudi_kartika_2024_10615261 %A KARTIKA, RUDI %A SULASTRI, LILIK %A KAMAL, ANDI SAPTAJI %A TARIGAN, ELSERA BR %A SIMANJUNTAK, PARTOMUAN %D 2024 %J GSC Advanced Research and Reviews %K Annona muricata %N 2 %P 240–246 %R 10.30574/gscarr.2023.17.2.0446 %T Identification of acetogenin compound, sabadelin from soursop seeds, Annona muricata (Annonaceae) %U https://gsconlinepress.com/journals/gscarr/content/identification-acetogenin-compound-sabadelin-soursop-seeds-annona-muricata-annonaceae %V 17 %X Isolation and identification of one chemical compound from the seeds of soursop, Annona muricata (Annonaceae) based on bioactivity-guided fractionation by the Brine Shrimp Lethality Assay (BSLA) have been done. The powder of soursop seed was extracted successively with n-hexane, chloroform, and methanol then the methanol extract was partitioned with ethylacetate water. Isolation and purification of ethylacetate extracts were carried out by column chromatography (SiO2; i. n-hexane-chloroform = 15:1 ~ 1:1 gave one pure isolatedcompound. Based on Ultra Violet (UV), Infra-Red (IR), Nuclear Magnetic Resonance (NMR), and mass spectra (LC-MS/MS), the isolated Fr-4 was an acetogenin compound, sabadelin which had a weak cytotoxicity LC50 of 487 ppm.

@article{rudi_kartika_2024_10615261, abstract = {Isolation and identification of one chemical compound from the seeds of soursop, Annona muricata (Annonaceae) based on bioactivity-guided fractionation by the Brine Shrimp Lethality Assay (BSLA) have been done. The powder of soursop seed was extracted successively with n-hexane, chloroform, and methanol then the methanol extract was partitioned with ethylacetate water. Isolation and purification of ethylacetate extracts were carried out by column chromatography [(SiO2; i. n-hexane-chloroform = 15:1 ~ 1:1 gave one pure isolatedcompound. Based on Ultra Violet (UV), Infra-Red (IR), Nuclear Magnetic Resonance (NMR), and mass spectra (LC-MS/MS), the isolated Fr-4 was an acetogenin compound, sabadelin which had a weak cytotoxicity LC50 of 487 ppm.}, added-at = {2024-03-14T12:07:35.000+0100}, author = {KARTIKA, RUDI and SULASTRI, LILIK and KAMAL, ANDI SAPTAJI and TARIGAN, ELSERA BR and SIMANJUNTAK, PARTOMUAN}, biburl = {https://www.bibsonomy.org/bibtex/2b9dc3d70dc865101d64a2f74d58df643/gscarrjournal}, doi = {10.30574/gscarr.2023.17.2.0446}, interhash = {5ce03de4e2f415a2a5da7964efe4d757}, intrahash = {b9dc3d70dc865101d64a2f74d58df643}, issn = {2582-4597}, journal = {GSC Advanced Research and Reviews}, keywords = {Annona muricata}, month = feb, number = 2, pages = {240–246}, timestamp = {2024-03-14T12:07:35.000+0100}, title = {Identification of acetogenin compound, sabadelin from soursop seeds, Annona muricata (Annonaceae)}, url = {https://gsconlinepress.com/journals/gscarr/content/identification-acetogenin-compound-sabadelin-soursop-seeds-annona-muricata-annonaceae}, volume = 17, year = 2024 }