Article,
Different Doses of Ketamine in Preventing Chills in Pregnant Lady with Caesarean Section Under Spinal Anesthesia
CENTRAL ASIAN JOURNAL OF MEDICAL AND NATURAL SCIENCE, 4 (2): 373-380 (February 2023)
Abstract
To compare the efficacy and safety of ketamine 0.25 mg/kg versus ketamine 0.5 mg/kg in the prevention of chills in patients undergoing caesarean section.
design: a prospective, randomized, double-blind, placebo-controlled study. In AL sader teaching hospital Mesaan .Iraq, and AL zahraa teaching hospital / Alnajaf alashraf.
patients: 120 pregnant women 1 and 2 in ASA body status who underwent cesarean section during spinal anesthesia.
procedures
Measurements: Patient characteristics, anesthesia and surgical details, 1 and 5 minute Apgar scores, and study drug side effects were recorded. Heart rate, mean arterial pressure, oxygen saturation by pulse oximetry, eardrum temperature, chills, and degree of sedation were recorded before intrathecal injection and every 5 minutes thereafter. Patients were randomized into three groups: saline (Group C, n=30), intravenous (IV) ketamine 0.25 mg/kg (Group K-0.25, n=30) or intravenous ketamine 0.5 mg/kg (group K-0.5, n=30). Grade 3 or 4 tremor was treated with 25 mg intravenous meperidine and prophylaxis was considered ineffective.
