Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.
%0 Journal Article
%1 smith2020halting
%A Smith, Kira
%D 2020
%I Openventio Publishers
%J Epidemiology Open Journal
%K Coronavirus Covid Covid-19 SIRT1 Sars Sirtuin Sirtuins Tenovin Tenovin-1 Tenovin-6 Treatment mTOR p53 Kira
%N 1
%P 13-15
%R 10.17140/EPOJ-5-119
%T Halting Coronavirus Replication
%U https://openventio.org/wp-content/uploads/Halting-Coronavirus-Replication-EPOJ-5-119.pdf
%V 5
%X Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.
@article{smith2020halting,
abstract = {Sirtuin 1 (SIRT1) inhibitors can reduce replication of many viruses with certain characteristics similar to those of coronaviruses, while the p53 protein is another important factor in the down-regulation of viral growth. Tenovin is a class of small molecules that inhibit Sirtuin 1 and 2, in addition to activating the p53 protein, by means of regulating the interactions used by coronaviruses as a self-defense mechanism. By blocking virus growth and continuous replication, with already tested antiviral medicines, the promise of coronavirus disease 2019 (COVID-19) eradication exists.},
added-at = {2021-03-31T15:54:09.000+0200},
author = {Smith, Kira},
biburl = {https://www.bibsonomy.org/bibtex/2cc790c23227aa876cf5643d158580cc5/kill4thethrill},
day = 05,
doi = {10.17140/EPOJ-5-119},
interhash = {c4d77cbbe6408f8739aceedfbabb2e30},
intrahash = {cc790c23227aa876cf5643d158580cc5},
issn = {2473-4780},
journal = {Epidemiology Open Journal},
keywords = {Coronavirus Covid Covid-19 SIRT1 Sars Sirtuin Sirtuins Tenovin Tenovin-1 Tenovin-6 Treatment mTOR p53 Kira},
language = {English},
month = {10},
number = 1,
pages = {13-15},
publisher = {Openventio Publishers},
timestamp = {2024-01-31T14:57:17.000+0100},
title = {Halting Coronavirus Replication},
url = {https://openventio.org/wp-content/uploads/Halting-Coronavirus-Replication-EPOJ-5-119.pdf},
volume = 5,
year = 2020
}