The aim of this study was to describe the epidemiology, aetiology, and clinical findings in dyskinetic cerebral palsy (CP)in a population-based follow-up study of children born between 1991 and 1998. Age range at ascertainment was 4 to 8 years and prevalence was 0.27 per 1000 live-births. Forty-eight children were examined (27 males, 21 females; mean age 9y, range 5-13y). Thirty-nine had dystonic CP and nine a choreo-athetotic subtype. Primitive reflexes were present in 43 children and spasticity in 33. Gross Motor Function Classification System levels were: Level IV, n= 10 and Level V, n= 28. The rate of learning disability (n= 35) and epilepsy (n= 30) increased with the severity of the motor disability. Thirty-eight children had anarthria. Peri- or neonatal adverse events had been present in 34 of 42 children born at >or=34 weeks' gestation. Motor impairment was most severe in this group. Placental abruption or uterine rupture had occurred in 8 participants and 19 of the 42 near-term/term children required assisted ventilation, compared with 1\% and 12\% respectively in other CP types. Neuroimaging in 39 children born at >or=34 weeks revealed isolated, late third trimester lesions in 24 and a combination of early and late third trimester lesions in seven. Dyskinetic CP is the dominant type of CP found in term-born, appropriate-for-gestational-age children with severe impairments who have frequently experienced adverse perinatal events.
%0 Journal Article
%1 Himmelmann2007
%A Himmelmann, K.
%A Hagberg, G.
%A Wiklund, L. M.
%A Eek, M. N.
%A Uvebrant, P.
%D 2007
%J Dev Med Child Neurol
%K Abruptio Placentae; Adolescent; Asphyxia Neonatorum; Brain; Cerebral Palsy; Child; Child, Preschool; Cross-Sectional Studies; Female; Follow-Up Humans; Hypoxia-Ischemia, Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Neurologic Examination; Population Surveillance; Pregnancy; Risk Factors; Sweden; Tomography, X-Ray Computed; Uterine Rupture
%N 4
%P 246--251
%R 10.1111/j.1469-8749.2007.00246.x
%T Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998.
%U http://dx.doi.org/10.1111/j.1469-8749.2007.00246.x
%V 49
%X The aim of this study was to describe the epidemiology, aetiology, and clinical findings in dyskinetic cerebral palsy (CP)in a population-based follow-up study of children born between 1991 and 1998. Age range at ascertainment was 4 to 8 years and prevalence was 0.27 per 1000 live-births. Forty-eight children were examined (27 males, 21 females; mean age 9y, range 5-13y). Thirty-nine had dystonic CP and nine a choreo-athetotic subtype. Primitive reflexes were present in 43 children and spasticity in 33. Gross Motor Function Classification System levels were: Level IV, n= 10 and Level V, n= 28. The rate of learning disability (n= 35) and epilepsy (n= 30) increased with the severity of the motor disability. Thirty-eight children had anarthria. Peri- or neonatal adverse events had been present in 34 of 42 children born at >or=34 weeks' gestation. Motor impairment was most severe in this group. Placental abruption or uterine rupture had occurred in 8 participants and 19 of the 42 near-term/term children required assisted ventilation, compared with 1\% and 12\% respectively in other CP types. Neuroimaging in 39 children born at >or=34 weeks revealed isolated, late third trimester lesions in 24 and a combination of early and late third trimester lesions in seven. Dyskinetic CP is the dominant type of CP found in term-born, appropriate-for-gestational-age children with severe impairments who have frequently experienced adverse perinatal events.
@article{Himmelmann2007,
abstract = {The aim of this study was to describe the epidemiology, aetiology, and clinical findings in dyskinetic cerebral palsy (CP)in a population-based follow-up study of children born between 1991 and 1998. Age range at ascertainment was 4 to 8 years and prevalence was 0.27 per 1000 live-births. Forty-eight children were examined (27 males, 21 females; mean age 9y, range 5-13y). Thirty-nine had dystonic CP and nine a choreo-athetotic subtype. Primitive reflexes were present in 43 children and spasticity in 33. Gross Motor Function Classification System levels were: Level IV, n= 10 and Level V, n= 28. The rate of learning disability (n= 35) and epilepsy (n= 30) increased with the severity of the motor disability. Thirty-eight children had anarthria. Peri- or neonatal adverse events had been present in 34 of 42 children born at >or=34 weeks' gestation. Motor impairment was most severe in this group. Placental abruption or uterine rupture had occurred in 8 participants and 19 of the 42 near-term/term children required assisted ventilation, compared with 1\% and 12\% respectively in other CP types. Neuroimaging in 39 children born at >or=34 weeks revealed isolated, late third trimester lesions in 24 and a combination of early and late third trimester lesions in seven. Dyskinetic CP is the dominant type of CP found in term-born, appropriate-for-gestational-age children with severe impairments who have frequently experienced adverse perinatal events.},
added-at = {2014-07-19T20:27:38.000+0200},
author = {Himmelmann, K. and Hagberg, G. and Wiklund, L. M. and Eek, M. N. and Uvebrant, P.},
biburl = {https://www.bibsonomy.org/bibtex/2c7b07350e76c30e895e24dd4d2eea204/ar0berts},
doi = {10.1111/j.1469-8749.2007.00246.x},
groups = {public},
interhash = {84736709bed6bce8a4bd119255ce7003},
intrahash = {c7b07350e76c30e895e24dd4d2eea204},
journal = {Dev Med Child Neurol},
keywords = {Abruptio Placentae; Adolescent; Asphyxia Neonatorum; Brain; Cerebral Palsy; Child; Child, Preschool; Cross-Sectional Studies; Female; Follow-Up Humans; Hypoxia-Ischemia, Infant; Infant, Newborn; Magnetic Resonance Imaging; Male; Neurologic Examination; Population Surveillance; Pregnancy; Risk Factors; Sweden; Tomography, X-Ray Computed; Uterine Rupture},
month = Apr,
number = 4,
pages = {246--251},
pii = {DMCN246},
pmid = {17376133},
timestamp = {2014-07-19T20:27:38.000+0200},
title = {Dyskinetic cerebral palsy: a population-based study of children born between 1991 and 1998.},
url = {http://dx.doi.org/10.1111/j.1469-8749.2007.00246.x},
username = {ar0berts},
volume = 49,
year = 2007
}