In living organisms, biofilms are defined as complex communities of bacteria residing within an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the cause of chronic, nosocomial, and medical device-related infections. Due to the antibiotic-resistant nature of biofilms, the use of antibiotics alone is ineffective for treating biofilm-related infections. In this review, we present a brief overview of concepts of bacterial biofilm formation, and current state-of-the-art therapeutic approaches for preventing and treating biofilms. Also, we have reviewed the prevalence of such infections on medical devices and discussed the future challenges that need to be overcome in order to successfully treat biofilms using the novel technologies being developed.
%0 Journal Article
%1 noauthororeditor
%A Khatoon, Zohra
%A McTiernan, Christopher D.
%A Suuronen, Erik J.
%A Mah, Thien-Fah
%A Alarcon, Emilio I.
%D 2018
%J Heliyon
%K 92c50-medical-applications-general 92c70-microbiology biofilm
%N 12
%P E01067
%R 10.1016/j.heliyon.2018.e01067
%T Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention
%U https://www.cell.com/heliyon/fulltext/S2405-8440(18)36901-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844018369019%3Fshowall%3Dtrue
%V 4
%X In living organisms, biofilms are defined as complex communities of bacteria residing within an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the cause of chronic, nosocomial, and medical device-related infections. Due to the antibiotic-resistant nature of biofilms, the use of antibiotics alone is ineffective for treating biofilm-related infections. In this review, we present a brief overview of concepts of bacterial biofilm formation, and current state-of-the-art therapeutic approaches for preventing and treating biofilms. Also, we have reviewed the prevalence of such infections on medical devices and discussed the future challenges that need to be overcome in order to successfully treat biofilms using the novel technologies being developed.
@article{noauthororeditor,
abstract = {In living organisms, biofilms are defined as complex communities of bacteria residing within an exopolysaccharide matrix that adheres to a surface. In the clinic, they are typically the cause of chronic, nosocomial, and medical device-related infections. Due to the antibiotic-resistant nature of biofilms, the use of antibiotics alone is ineffective for treating biofilm-related infections. In this review, we present a brief overview of concepts of bacterial biofilm formation, and current state-of-the-art therapeutic approaches for preventing and treating biofilms. Also, we have reviewed the prevalence of such infections on medical devices and discussed the future challenges that need to be overcome in order to successfully treat biofilms using the novel technologies being developed.},
added-at = {2023-10-25T00:20:49.000+0200},
author = {Khatoon, Zohra and McTiernan, Christopher D. and Suuronen, Erik J. and Mah, Thien-Fah and Alarcon, Emilio I.},
biburl = {https://www.bibsonomy.org/bibtex/2be4e4cd3ff1009de7e6321062d9e559e/gdmcbain},
doi = {10.1016/j.heliyon.2018.e01067},
interhash = {f645f0cd22daa8ff2b86deb9ae4024b8},
intrahash = {be4e4cd3ff1009de7e6321062d9e559e},
journal = {Heliyon},
keywords = {92c50-medical-applications-general 92c70-microbiology biofilm},
number = 12,
pages = {E01067},
timestamp = {2023-10-25T00:20:49.000+0200},
title = {Bacterial biofilm formation on implantable devices and approaches to its treatment and prevention},
url = {https://www.cell.com/heliyon/fulltext/S2405-8440(18)36901-9?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2405844018369019%3Fshowall%3Dtrue},
volume = 4,
year = 2018
}